OsteoSync Ti is a best-in-class, cost-effective, highly porous titanium scaffold material for improved implant fixation. Its material properties can be engineered to serve a variety of applications. The version developed for implant-bone attachment has the following properties:
OsteoSync Ti Products
The SITES Medical engineers also found clever ways to bond the material to a variety of metal and polymer substrates, including titanium, cobalt-chrome, zirconium, PEEK, polycarbonate urethane and UHMWPE, making this a platform technology with a wide range of applications.
In comparative testing, OsteoSync Ti had a higher friction coefficient than the leading competitor demonstrating the material’s capability for providing initial implant stability and enabling long-term fixation.
OsteoSync Ti also demonstrated the lowest abrasion debris generation on implant insertion, reducing the potential for debris-related inflammation or implant damage.
Canine OsteoSync Hip Study
In pre-clinical testing, OsteoSync Ti coated implants demonstrated 75% of void space to be occupied by bone, nearly twice that of competing technologies, which literature shows to be in the range of 24-38% at the same 12 week follow up period.
Canine OsteoSync Ti Pin Study
In pre-clinical testing using a static model, OsteoSync Ti coated implants demonstrated 90-100% bone volume ingrowth at 6 weeks follow-up. OsteoSync™ Ti has bone volume ingrowth ~2X – 5X greater than 3D printed ingrowth materials at similar timeframes.
Canine OsteoSync Ti/PCU Cartilage Plug Study
In pre-clinical testing using a dynamic model, OsteoSync Ti coated implants demonstrated 90-100% bone volume ingrowth at 11 weeks follow-up. OsteoSync™ Ti has bone volume ingrowth ~2X – 5X greater than 3D printed ingrowth materials at similar timeframes.
Bone Attachment Shear Strength
In pre-clinical testing, OsteoSync Ti coated implants demonstrated bone attachment shear strength 1.8 times greater than titanium plasma spray devices and 6.8 times greater than PEEK devices at the 5 week follow up period.
Scaffolds with higher porosity, larger pore size, and open pore structure are associated with greater bone ingrowth. Nanoscale structures in combination with micron-/submicron-scale roughness improves osteoblast differentiation and local factor production, which, in turn, indicates the potential for faster healing times and improved implant osseointegration in vivo.